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Mallory Smith’s Story: A Legacy That Continues
A rare disease, a young patient and a continuing legacy 29 February 2020, the last day of that month, was Rare Disease Day, an initiative launched by the European rare disease organization EURORDIS in 2008. Because these…
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Taking on Tuberculosis: Graham Hatfull and His Phage Kingdom
1. Building a kingdom Mycobacteria are an ancient and difficult group of pathogens. They include Mycobacterium tuberculosis, which causes tuberculosis; Mycobacterium leprae, which causes leprosy; and nontuberculous…
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Treating Disease with Viruses: Hope for the Post-Antibiotic Era?
Before setting off for the Shanghai Institute of Phage and AMR on the outskirts of the city, interns from elsewhere receive an unusual request: bring a bottle of wastewater from home. A bottle of water from a sewer or drainage…
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Félix d’Herelle: A Pioneer of Phage Therapy
On 10 September 1917, 44-year-old Félix d’Herelle published a short paper in the prestigious Comptes Rendus de l’Académie des Sciences. It described a new microorganism—an obligate intracellular parasite of bacteria—which he…
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